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We are dedicated to making a real difference in the lives of patients around the world.  We realise that in order to accomplish this, we need talented, motivated individuals who believe in this mission and who seek excellence in their work.  We are therefore committed to providing outstanding rewards for your contributions, a world-class working environment, and opportunities for career development.

Ranked the world's top city for quality of life for consecutive years (2009-2012), Vienna offers an attractive, varied and international environment.


Scientist in Phage Display

Posting date: 06 January 2014

Dutalys is a privately owned antibody technology company based in Vienna, Austria. We are a small and highly motivated team of people with a shared commitment to channel state-of-the-art empirical and computational approaches towards creating effective antibody drugs for the treatment of serious and life- threatening diseases. We are offering an excellent opportunity to work on antibody engineering together with experienced scientists in the field.

We currently have an opening for a Post-doc/Scientist in Phage Display, who will focus on the selection, screening and optimization of bispecific antibodies against a variety of therapeutic targets. The position will be graded as Associate Scientist, Scientist or Senior Scientist depending on the experience of the successful candidate.

Responsibilities:

  • Generate therapeutic bispecific antibodies
  • Devise phage selection strategies and design selection arms
  • Perform phage selections using manual and automated techniques
  • Perform high-throughput screening using ELISA automation
  • Express and purify selected antibody clones in E.coli
  • Perform affinity maturation and optimization of antibodies
  • Participate in the development of new antibody technology

Requirements:

Above all, we are looking for a talented scientist who possesses excellent scientific qualities, in particular, thoroughness and attention to detail. In addition, the candidate should have:

  • At least 2 years of hands-on research experience in protein phage display, protein engineering, in vitro evolution or bio-molecular interaction studies
  • Thorough understanding of the mathematics that underlie the kinetics of protein-protein interaction
  • Experience in the day-to-day cloning of cDNAs, protein expression in E.coli and basic protein chemistry such as affinity purification and Western Blotting
  • Ability to accurately record and effectively communicate scientific data and ideas in English
  • Commitment to keeping abreast of the latest literature in the field of phage display

Experience in affinity maturation and in the cloning of libraries would be of advantage.

If this opportunity excites you and you believe that you are qualified for this position,, please submit your resume, including contact details for 2 referees, and cover letter to [email protected]